Macular hole: diagnosis and treatment

Treatment for macular hole

The only way to treat a macular hole is with an operation. Eye drops, lasers, or glasses will not close a macular hole.

Sometimes, a very small macular hole might close on its own, or with an injection into the eye, but this is not common. Your eye doctor will help you decide if surgery is right for you. If your symptoms are mild and not affecting your daily life, you might not need surgery straight away. However, if the hole is getting bigger or your vision is getting worse, surgery is usually recommended to prevent further vision loss and improve your sight.

Surgery for macular hole

What does the operation involve?

The surgery to repair a macular hole is called a vitrectomy. It's done by a specialist eye surgeon.

The procedure usually takes about 30 to 60 minutes. Most often, we do it under local anaesthetic. This means your eye is numbed, and you stay awake but comfortable. You won't see the details of what's happening, but you might be aware of bright lights. Sometimes, we may use a general anaesthetic, where you are asleep. Your surgeon will discuss the best option for you.

  1. During the vitrectomy:
    Tiny incisions: The surgeon makes three very small cuts (less than 1mm) in the white part of your eye. These usually don't need stitches.
  2. Removing the vitreous gel: A tiny instrument is used to remove the jelly-like substance (vitreous gel) from the middle of your eye. This is replaced with a clear saline solution during the surgery.
  3. Peeling the membrane: The surgeon may peel a very thin, innermost layer of the retina called the internal limiting membrane (ILM). This helps to relieve any pulling forces on the macula and encourages the hole to close.
  4. Gas bubble: At the end of the surgery, a special gas or air bubble is put inside your eye. This bubble acts like an internal bandage, gently pressing on the edges of the macular hole to help it close and heal. The gas bubble will gradually disappear over time (see 'Types of Gas and What to Expect').
  5. During the vitrectomy procedure the medicine Triamcinolone
    Acetonide may be used as an aid to visualise the vitreous. This medicine is being used as an “unlicensed product” but has been used at Moorfields for this purpose for decades. For more information visit our pages on unlicensed medicines, or discuss with your clinician if you have any questions.

What are the benefits of surgery?

The main aim of surgery is to close the macular hole and improve your central vision, especially your reading vision.

  • High success rate for closure: For most macular holes, there is a very high chance (around 90-95%) that the hole will close after one operation. Success rates are generally better for smaller holes and those that haven't been present for a long time.
  • Improved vision: Many patients (over 70%) experience an improvement in their central visual acuity, often by 2 or 3 lines on a vision chart.
  • Reduced distortion: The wavy or distorted vision often improves
    significantly once the hole is closed.
  • Stabilisation: Surgery prevents the hole from getting larger and your vision from getting worse due to the macular hole.

Vision improvement can be slow. It may take many months, sometimes up to a year, to see the full benefit of the surgery. Complete restoration of vision is not possible, especially for larger or long-standing holes.

Anaesthesia for your operation

Most operations for macular holes are performed under a local anaesthetic, which means you will be awake throughout your operation. We will inject local anaesthetic into the area around your eye to numb your eye and prevent you from feeling any pain during the operation. You will not be able to see details of what is happening, but you might be aware of the bright lights or movement in the operating theatre. During the operation, we will ask you to lie as flat as possible and keep your head still.

General anaesthesia, under which you are asleep for the whole operation, is rarely used for macular hole surgery. If you require a general anaesthetic, you will need to follow specific instructions about eating and drinking prior to your operation.

Your operation

The operation to repair your macular hole is called a vitrectomy and usually takes about an hour. Whichever form of anaesthetic you chose, we will give you eye drops before your operation to enlarge your pupils. The surgeon will then make tiny openings in your eye and remove the vitreous (the jelly-like substance) from inside. Your eye is then filled with a bubble of special gas, which presses against the macula and seals the hole.

If we put a gas or air bubble in your eye you must not fly for the periods of time specified below. This is because the gas or air bubble will expand in size and can lead to raised pressure inside your eye, leading to visual loss.

We use three types of gases:

  • C3F8 which is long acting and can stay in your eye for up to 12 weeks.
  • SF6 which can stay in your eye for up to four weeks.
  • C2F6 which can stay in your eye for up to eight weeks.
  • Air – which can stay in your eye for up to two weeks.

You will be told after your surgery which type of gas bubble was used. The surgeon might put small stitches in your eye to close up the opening. The stitches dissolve naturally over about four to six weeks. At the end of the operation, we usually put a pad and shield over your eye to protect it. These will be removed the morning after your surgery.

Recovery

After your operation – how your eye will feel

Your eye will feel uncomfortable, gritty, and itchy. It might appear red or bruised and the vision is likely to be very poor at first. This is normal for seven to 14 days. We will give you eye drops to reduce inflammation and to prevent infection, and will explain how and when you should use them. You can also take paracetamol for pain relief as advised on the packet. Please do not rub your eye. Your eye will take between two and six weeks to heal, but your vision might continue to improve for several months.

Your vision

Your vision will be very poor with the gas in your eye. As the gas disperses and is replaced by your eye’s natural fluid, you will begin to see a line, which wobbles in your vision, like a spirit level. You will be able to see above the line, but the vision will be fuzzy underneath. This line will continue to ease downwards until only a tiny bubble is left and finally, it too will disappear.

It is important to note that the gas can react with another gas called nitrous oxide, which can cause problems in your eye if any is administered. Nitrous oxide is commonly used during childbirth and in A&E as pain relief. Please tell the midwife or A&E staff treating you (or ask your family to) that you have gas in your eye and that they should not administer any nitrous oxide. Should you need a general anaesthetic for any reason during this time it is important that you also tell the anaesthetist that you have had surgery and gas in your eye.

Posturing

This is the hardest part of the recovery following your surgery, but the most important. If we put gas or silicone oil in your eye, we usually ask you to “posture” for up to seven days. This means lying or sitting in a position that keeps your face down (so that the bubble floats up and presses the retina into position while it is healing).

Your surgeon will advise you if it is necessary for you to posture after your surgery, and will give you another information to show you how to do this.

Risks

What are the risks of macular hole surgery?

All surgery carries some risks, but serious complications are rare with macular hole surgery. Your surgeon will explain these risks fully.

Common and less serious risks:

  • Temporary discomfort and redness: Your eye might feel gritty, watery, and look red for a few days or weeks. Paracetamol can help with any mild pain.
  • Bruising around the eye: This is common and will go away quickly.
  • Temporary blurred vision: Your vision will be very blurry straight after surgery due to the gas bubble.
  • Increased eye pressure: This is usually temporary and often controlled with eye drops. Rarely, some people may need ongoing eye drops or further treatment to manage it.
  • Cataract formation: Vitrectomy surgery almost always speeds up the development of a cataract (clouding of your eye's natural lens), especially if you are over 50. This usually happens within 6 to 12 months. You may need cataract surgery in the future.
  • Sometimes, your surgeon might suggest removing the cataract at the same time as your macular hole surgery.

More serious (but rare) risks:

  • Retinal detachment: This is a serious problem where the retina comes away from the back of the eye. It can lead to severe vision loss if not treated quickly. The risk is low, about 1 to 2 in 100 people. If this happens, you would need another operation to fix it.
  • Infection (endophthalmitis): A very rare (about 1 in 2,000 cases) but serious complication that can cause severe vision loss. We give you antibiotic drops to reduce this risk.
  • Bleeding inside the eye: This is rare.
  • Macular hole does not close (failure): In about 5-10% of cases, the macular hole may not close after the first surgery. This risk is higher for larger holes. If this happens, further surgery might be considered.
  • Macular hole re-opening: Rarely, a closed macular hole can re-open weeks or months after surgery.
  • No improvement or worsening vision: In some cases, vision may not improve, or it could even get worse, especially if the macula was severely damaged before surgery. The risk of vision being worse than before surgery is low (less than 1 in 50 people).
  • Loss of the eye: This is extremely rare.

Macular hole treatment is available at Moorfields Private

You can self-fund or use private medical insurance to fund your treatment.

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